For the third time in a century, the United States is seriously considering its place among the world’s nations. The current debate, in some ways, is more far-ranging than those that occurred after World Wars I and II because it encompasses not just membership in particular organizations but our general approach to the world at large. The issue has profound implications, for it raises the fundamental question: Who governs? This first annual AEI conference on the subject will address the extent to which America’s freedom of action internationally and its own internal governance--its sovereignty and its constitutionalism--should be constrained by international organizations and agreements.